Publications · PQC-Huanglab

Nature Communications2026

YTHDC1 functions as a molecular chaperone to suppress ALS-linked hnRNPA1 mutants from aggregation

Kang Ren, Mingjie Cheng, Qiudan Luo, Boxin Zhang, Haosheng Zhang, Zhe Li, Yuxin Liu, Yujie Wang, Ting Kang, Xiaoming Dai, Jiong Chen, Yuanming Cheng & Liangqian Huang

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Nature2021

DAXX represents a new type of protein-folding enabler

Huang L, Agrawal T, Zhu G, Yu S, Tao L, Lin J, Marmorstein R, Shorter J, and Yang X

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Cell Reports2020

TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson's Disease

Zhu G, Harischandra DS, Ghaisas S, Zhang P, Prall W, Huang L, Maghames C, Guo L, Luna E, Mack KL, Torrente MP, Luk KC, Shorter J, Yang X.

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Scientific Reports2016

Interaction with Pyruvate Kinase M2 Destabilizes Tristetraprolin by Proteasome Degradation and Regulates Cell Proliferation in Breast Cancer

Huang L, Yu Z, Zhang Z, Ma W, Song S, Huang G.

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Biochemical and Biophysical Research Communications cover

Biochem Biophys Res Commun2016

PKM2 Thr454 phosphorylation increases its nuclear translocation and promotes xenograft tumor growth in A549 human lung cancer cells

Yu Z, Huang L, Qiao P, Jiang A, Wang L, Yang T, Tang S, Zhang W, Ren C

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PLoS One2014

HSP40 interacts with pyruvate kinase M2 and regulates glycolysis and cell proliferation in tumor cells

Huang L, Yu Z, Zhang T, Zhao X, Huang G.

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Cell Signal2014

Using a yeast two-hybrid system to identify FTCD as a new regulator for HIF-1 in HepG2 cells

Yu Z, Ge Y, Xie L, Zhang T, Huang L, Zhao X, Liu J, Huang G.

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PLoS One2014

A regulatory feedback loop between HIF-1 and PIM2 in HepG2 cells

Yu Z, Zhao X, Ge Y, Zhang T, Huang L, Zhou X, Xie L, Liu J, Huang G.

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J Biol Chem2013

Proviral insertion in murine lymphomas 2 (PIM2) oncogene phosphorylates pyruvate kinase M2 (PKM2) and promotes glycolysis in cancer cells

Yu Z, Zhao X, Huang L, Zhang T, Yang F, Xie L, Song S, Miao P, Zhao L, Sun X, Liu J, Huang G.

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Selected Publications